Pharyngula, a site run by an evo-devo scientist P.Z. Meyers, is probably the largest science site on the web. He gets mucho hits. Here he goes over all the people who are in his killfile, blocking them from posting to his comments (there are usually 100s per post). He is also a rabid atheist (I mean rabid in the good sense), so he gets lots of "God's Children" clogging up the stupid meters.
Its hard work at the top.